The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 24, 2023

Filed:

May. 17, 2019
Applicant:

Rosalind Franklin University of Medicine and Science, North Chicago, IL (US);

Inventor:

Joanna Dabrowska, North Chicago, IL (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/16 (2006.01); A61B 5/00 (2006.01); A61B 5/145 (2006.01); A61K 38/095 (2019.01); A61K 9/00 (2006.01); A61P 25/22 (2006.01);
U.S. Cl.
CPC ...
A61B 5/165 (2013.01); A61B 5/14528 (2013.01); A61B 5/16 (2013.01); A61B 5/162 (2013.01); A61B 5/4848 (2013.01); A61B 5/4884 (2013.01); A61B 5/7246 (2013.01); A61K 9/0043 (2013.01); A61K 38/095 (2019.01); A61P 25/22 (2018.01);
Abstract

A method and system is provided for determining a discrimination index in a subject that may be suffering from or at risk for a stress-induced psychiatric disorder. The discrimination index may be equal to a ratio of a subject's cued fear response and non-cued fear response measured during a fear-potentiated startle (FPS) paradigm. Such a value may allow a physician or researcher to quantify how well a subject discriminates between signaled (cued) fear and un-signaled (non-cued) fear, which may be a biomarker for psychiatric disorders like post-traumatic stress disorder, panic disorder, phobias, and/or generalized anxiety disorder. The determined discrimination index may provide a standardized way of diagnosing and evaluating mental illnesses, more uniform treatment of patients, and/or more precise monitoring and evaluation of treatment efficacy.


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