The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 17, 2023
Filed:
Sep. 18, 2020
Applicant:
On Target Laboratories, Inc., West Lafayette, IN (US);
Inventors:
Sumith A. Kularatne, West Lafayette, IN (US);
Mini Thomas, West Lafayette, IN (US);
Assignee:
ON TARGET LABORATORIES, INC., West Lafayette, IN (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); G01N 33/58 (2006.01); C09B 23/01 (2006.01); G01N 33/574 (2006.01); C07D 311/90 (2006.01); C07D 209/12 (2006.01); A61B 1/00 (2006.01); A61B 1/04 (2006.01); A61B 5/00 (2006.01); C09B 23/16 (2006.01); G01N 33/573 (2006.01); A61K 49/00 (2006.01); A61B 90/30 (2016.01); A61B 90/00 (2016.01); A61B 90/20 (2016.01); A61B 90/50 (2016.01);
U.S. Cl.
CPC ...
G01N 33/583 (2013.01); A61B 1/00009 (2013.01); A61B 1/043 (2013.01); A61B 5/0071 (2013.01); A61B 5/0073 (2013.01); A61B 5/0084 (2013.01); A61B 5/7282 (2013.01); C07D 209/12 (2013.01); C07D 311/90 (2013.01); C09B 23/0008 (2013.01); C09B 23/0025 (2013.01); C09B 23/0066 (2013.01); C09B 23/166 (2013.01); C12Y 402/01001 (2013.01); G01N 33/573 (2013.01); G01N 33/574 (2013.01); G01N 33/57484 (2013.01); G01N 33/582 (2013.01); A61B 90/20 (2016.02); A61B 90/30 (2016.02); A61B 2090/373 (2016.02); A61B 2090/502 (2016.02); A61B 2560/0431 (2013.01); A61K 49/0017 (2013.01); A61K 49/0032 (2013.01); G01N 2333/988 (2013.01);
Abstract
The present disclosure relates to compounds that are useful as near-infrared fluorescence probes, wherein the compounds include i) a ligand that binds to the active site of carbonic anhydrase, ii) a dye molecule, and iii) a linker molecule that comprises an amino acid, amide, ureido, or polyethylene glycol derivative thereof. The disclosure further describes methods and compositions for making and using the compounds, methods incorporating the compounds, and kits incorporating the compounds.