The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 17, 2023

Filed:

May. 14, 2019
Applicant:

The Usa, As Represented BY the Secretary, Dept. of Health and Human Services, Bethesda, MD (US);

Inventors:

Majda Haznadar, Bethesda, MD (US);

Ewy Mathe, Bethesda, MD (US);

Andrew D. Patterson, Bethesda, MD (US);

Curtis Craig Harris, Bethesda, MD (US);

Frank Gonzalez, Bethesda, MD (US);

Kristopher Krausz, Bethesda, MD (US);

Soumen Manna, Bethesda, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
G01N 33/57423 (2013.01); G01N 33/5743 (2013.01); G01N 33/57488 (2013.01); G01N 2400/00 (2013.01); G01N 2800/52 (2013.01);
Abstract

The present invention provides methods and materials for diagnosing cancer in an individual using a tissue, blood or urine sample from the patient. Specifically, the disclosed method comprises determining the level of one or more metabolite selected from the group consisting of creatine riboside, metabolite 561+, cortisol sulfate and N-acetylneuraminic acid. The present invention also provides a method for determining the prognosis of a cancer patient by determining the level of one or more metabolite selected from the group consisting of creatine riboside, metabolite 561+, cortisol sulfate and N-acetylneuraminic acid. Also provided are kits for detecting cancer or determining the prognosis of a cancer patient.


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