The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 17, 2023
Filed:
Nov. 30, 2018
Applicant:
Oslo Universitetssykehus Hf, Oslo, NO;
Inventors:
Guro E. Lind, Oslo, NO;
Marine Jeanmougin, Oslo, NO;
Heidi D. Pharo, Oslo, NO;
Kim Andresen, Nesbru, NO;
Ragnhild Lothe, Oslo, NO;
Assignee:
OSLO UNIVERSITETSSYKEHUS HF, Oslo, NO;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6886 (2018.01); C12Q 1/686 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); C12Q 1/686 (2013.01); C12Q 2523/125 (2013.01); C12Q 2545/114 (2013.01); C12Q 2561/101 (2013.01); C12Q 2563/107 (2013.01); C12Q 2600/154 (2013.01); C12Q 2600/166 (2013.01);
Abstract
The present invention provides a method of quantification of a target nucleic acid, using at least any two of the genes SYT10, EPHA3, PLEKHF1 and KBTBD4 as control genes. In particular, the combination of the genes SYT10, EPHA3, PLEKHF1 and KBTBD4, known as the 4Plex, is provided as a control for nucleic acid quantification. The 4Plex has particular utility as a control for nucleic acid quantification by methylation-specific droplet digital PCR.