The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 17, 2023
Filed:
Nov. 08, 2018
Shanghai Hyamab Biotech Co., Ltd., Shanghai, CN;
Heng Pan, Shanghai, CN;
Haohan Liu, Shanghai, CN;
Yingying Gao, Shanghai, CN;
Shaoping Hu, Shanghai, CN;
Yong Li, Shanghai, CN;
Mingming Pan, Shanghai, CN;
Tatchi Teddy Yang, Shanghai, CN;
Qing Duan, Shanghai, CN;
Lile Liu, Shanghai, CN;
Shanghai Hyamab Biotech Co., Ltd., Shanghai, CN;
Abstract
Provided in the present invention are a 4-1BB antibody and a preparation method and the use thereof. In particular, provided in the present invention are a 4-1BB antibody, which has high affinity to 4-1BB protein, can effectively activate the signal downstream of the 4-1BB and significantly increase expression quantities of IFN-γ and IL-2 in human mixed lymphocytes or T lymphocytes, and can be used to treat cancers and autoimmune diseases.