The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 17, 2023
Filed:
Dec. 18, 2019
23andme, Inc., Sunnyvale, CA (US);
Yu Chen, Foster City, CA (US);
Chingwei Vivian Lee, Foster City, CA (US);
Germaine Fuh-Kelly, Pacifica, CA (US);
Zuoan Yi, Mountain View, CA (US);
Yao-ming Huang, San Mateo, CA (US);
Valentine Yeung, Belmont, CA (US);
Krista Maureen McCutcheon, Burlingame, CA (US);
Samuel Nalle, Pacifica, CA (US);
Augusta Eleanor Broughton, Fresno, CA (US);
Louise Scharf, Redwood City, CA (US);
Navneet Singh, San Francisco, CA (US);
Tina Thai, San Mateo, CA (US);
Shouhua Xiao, Foster City, CA (US);
23andMe, Inc., Sunnyvale, GA (US);
Abstract
The present disclosure provides binding proteins, such as antibodies and antigen-binding fragments, which specifically bind to human CD96 receptor protein (hu-CD96) and are capable of decreasing, inhibiting, and/or fully-blocking immune regulatory effects mediated by hu-CD96. The present disclosure also provides methods of using the antibodies (and compositions thereof) to treat diseases and conditions responsive to decreasing, inhibiting and/or blocking immune regulatory function or activity mediated by CD96 binding to CD155, including effects arising from CD96 interactions with CD226 and/or TIGIT.