The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 17, 2023
Filed:
Mar. 23, 2020
Applicant:
Albumedix Ltd, Nottingham, GB;
Inventors:
Christopher John Arthur Finnis, Nottingham, GB;
Joanna Mary Hay, Nottingham, GB;
Esben Peter Friis, Herlev, DK;
Jason Cameron, Nottingham, GB;
Darrell Sleep, Nottingham, GB;
Assignee:
ALBUMEDIX, LTD, Nottingham, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/765 (2006.01); G16B 5/00 (2019.01); C07K 14/76 (2006.01);
U.S. Cl.
CPC ...
C07K 14/765 (2013.01); C07K 14/76 (2013.01); G16B 5/00 (2019.02); C07K 2319/00 (2013.01);
Abstract
Based on the three-dimensional structure of albumin, the inventors have designed variant polypeptides (muteins) which have one or more cysteine residues with a free thiol group (hereinafter referred to as 'thio-albumin'). The variant polypeptide may be conjugated through the sulphur atom of the cysteine residue to a conjugation partner such as a bioactive compound.