The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 17, 2023
Filed:
Aug. 26, 2020
Applicant:
The Johns Hopkins University, Baltimore, MD (US);
Inventors:
Jun Liu, Baltimore, MD (US);
Jingxin Wang, Baltimore, MD (US);
Zhaoli Sun, Baltimore, MD (US);
Sam Hong, Baltimore, MD (US);
Assignee:
The Johns Hopkins University, Baltimore, MD (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 5/103 (2006.01); C07D 498/18 (2006.01); C07D 519/00 (2006.01); A61K 47/54 (2017.01); A61K 38/07 (2006.01);
U.S. Cl.
CPC ...
C07K 5/1008 (2013.01); A61K 38/07 (2013.01); A61K 47/545 (2017.08); C07D 498/18 (2013.01); C07D 519/00 (2013.01);
Abstract
A compound of Formula I, and its analogs are provided. Compositions that include Formula I can be used to inhibit human equilibrative nucleoside transporter 1, increase adenosine signaling and produce effects that include increasing antiviral activity, increasing antiparasitic activity, increasing alcohol tolerance, decreasing pain protecting from ischemia as well as many other conditions.