The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 17, 2023

Filed:

Sep. 26, 2018
Applicant:

Bayer Healthcare Llc, Indianola, PA (US);

Inventor:

Kathryn Kwant, Oakland, CA (US);

Assignee:

Bayer HealthCare LLC, Whippany, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/14 (2006.01); C07K 16/00 (2006.01); C12P 21/00 (2006.01); C07K 1/113 (2006.01); C07K 16/06 (2006.01);
U.S. Cl.
CPC ...
C07K 1/1133 (2013.01); C07K 1/145 (2013.01); C07K 16/00 (2013.01); C07K 16/065 (2013.01); C12P 21/00 (2013.01); C12N 2501/999 (2013.01);
Abstract

This disclosure relates to methods for the prevention of the reduction of disulfide bonds in a polypeptide expressed in a recombinant host cell, comprising, following fermentation, adding selenite and/or its salts or derivatives to a harvest solution of the recombinant host cell, wherein the disulfide bond in the polypeptide remains non-reduced.


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Quick Actions:

Kwant, Kathryn. (2023). Methods for preventing disulfide bond reduction in cell culture harvest with selenite (U.S. Patent No. 11555052). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11555052

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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