The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 17, 2023
Filed:
Jul. 13, 2020
Kura Oncology, Inc., San Diego, CA (US);
The Regents of the University of Michigan, Ann Arbor, MI (US);
Tao Wu, Carlsbad, CA (US);
Liansheng Li, San Diego, CA (US);
Yi Wang, San Diego, CA (US);
Pingda Ren, San Diego, CA (US);
Jolanta Grembecka, Ann Arbor, MI (US);
Tomasz Cierpicki, Ann Arbor, MI (US);
Szymon Klossowski, Ann Arbor, MI (US);
Jonathan Pollock, Ann Arbor, MI (US);
Dmitry Borkin, Ann Arbor, MI (US);
KURA ONCOLOGY, INC., San Diego, CA (US);
THE REGENTS OF THE UNIVERSITY OF MICHIGAN, Ann Arbor, MI (US);
Abstract
The present disclosure provides compounds of Formula (I-A) for inhibiting the interaction of menin with MLL1, MLL2 and MLL-fusion oncoproteins. The compounds are useful for the treatment of leukemia, solid cancers, diabetes and other diseases dependent on activity of MLL1, MLL2, MLL fusion proteins, and/or menin.