The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 17, 2023
Filed:
Jul. 06, 2018
The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Bethesda, MD (US);
Christopher Ramsden, Baltimore, MD (US);
Gregory Keyes, Baltimore, MD (US);
Abstract
This disclosure concerns fatty acid derivatives, pharmaceutical compositions comprising the fatty acid derivatives, and methods of using the fatty acid derivatives, for example, to treat inflammation, chronic itch, chronic pain, an autoimmune disorder, atherosclerosis, a skin disorder, arthritis, a neurodegenerative disorder, or a psychiatric disorder in a subject. In some embodiments, the fatty acid derivative is a compound, or a stereoisomer, tautomer, or pharmaceutically acceptable salt thereof, having a structure according to: wherein X is from 1-16 carbons in length, Z is aliphatic from 1-16 carbons in length, or is not present, Y is selected from: R, R, and Rare independently hydrogen or lower alkyl, Ris lower alkyl, hydroxyl, carboxyl, or amine, Ris hydrogen, lower alkyl, or halide, Ris hydroxyl or substituted thiol, and each Ris independently hydrogen or fluoride or is not present and the adjacent carbons form alkyne.