The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 17, 2023
Filed:
Dec. 29, 2017
University of Central Florida Research Foundation, Inc., Orlando, FL (US);
Hesperos, Inc., Orlando, FL (US);
James Hickman, Orlando, FL (US);
Alisha Colon, Orlando, FL (US);
Christopher McAleer, Orlando, FL (US);
Trevor Sasserath, Orlando, FL (US);
John Rumsey, Orlando, FL (US);
Daniel Elbrecht, Orlando, FL (US);
University of Central Florida Research Foundation, Inc., Orlando, FL (US);
Hesperos, Inc., Orlando, FL (US);
Abstract
A pumpless microfluidic system is disclosed that can be used to mimic the interaction of organ systems with the immune system. Also disclosed is a method for mimicking an immune system, comprising culturing a plurality of organ cells and at least one population of immune cells in the disclosed pumpless microfluidic system under physiological conditions. The method can further comprise activating an immune reaction in the pumpless microfluidic system, continuing the culture for a defined period, collecting a sample of culture medium from the system, and assaying the sample for one or more indicators of an immune response.