The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 17, 2023
Filed:
Jul. 31, 2019
Applicant:
Bristol-myers Squibb Company, Princeton, NJ (US);
Inventors:
Yam B. Poudel, Fremont, CA (US);
Sanjeev Gangwar, Foster City, CA (US);
Liqi He, San Jose, CA (US);
Prasanna Sivaprakasam, Lawrenceville, NJ (US);
Matthias Broekema, New Hope, PA (US);
Matthew Cox, San Francisco, CA (US);
Christine M. Tarby, Lawrenceville, NJ (US);
Qian Zhang, Danville, CA (US);
Naidu S. Chowdari, Sunnyvale, CA (US);
Assignee:
Bristol-Myers Squibb Company, Princeton, NJ (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/519 (2006.01); A61K 47/60 (2017.01); A61K 39/395 (2006.01); A61P 35/00 (2006.01); A61K 31/395 (2006.01);
U.S. Cl.
CPC ...
A61K 31/519 (2013.01); A61K 31/395 (2013.01); A61K 39/3955 (2013.01); A61K 39/39558 (2013.01); A61K 47/60 (2017.08); A61P 35/00 (2018.01); C07D 487/04 (2013.01);
Abstract
Compounds according to formula I are useful as agonists of Toll-like receptor 7 (TLR7). Such compounds can be used in cancer treatment, especially in combination with an anti-cancer immunotherapy agent, or as a vaccine adjuvant.