The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 10, 2023

Filed:

Nov. 02, 2020
Applicant:

Genomic Health, Inc., Redwood City, CA (US);

Inventors:

Steven Shak, Hillsborough, CA (US);

George Andrew Watson, Los Altos, CA (US);

Michael R. Crager, Menlo Park, CA (US);

Tara Maddala, Sunnyvale, CA (US);

Margarita Lopatin, Palo Alto, CA (US);

Audrey Goddard, San Francisco, CA (US);

Dejan Knezevic, Palo Alto, CA (US);

Christer Svedman, Stockholm, SE;

Assignee:

Genomic Health, Inc., Redwood City, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); G16B 20/20 (2019.01); G16B 20/00 (2019.01); G16C 99/00 (2019.01); C12Q 1/6886 (2018.01); G16H 50/30 (2018.01); G16Z 99/00 (2019.01);
U.S. Cl.
CPC ...
G16B 20/20 (2019.02); C12Q 1/6886 (2013.01); G16B 20/00 (2019.02); G16C 99/00 (2019.02); G16H 50/30 (2018.01); G16Z 99/00 (2019.02); C12Q 2600/118 (2013.01); C12Q 2600/158 (2013.01);
Abstract

The present invention provides algorithm-based molecular assays that involve measurement of expression levels of genes from a biological sample obtained from a kidney cancer patient. The present invention also provides methods of obtaining a quantitative score for a patient with kidney cancer based on measurement of expression levels of genes from a biological sample obtained from a kidney cancer patient. The genes may be grouped into functional gene subsets for calculating the quantitative score and the gene subsets may be weighted according to their contribution to cancer recurrence.


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