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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11549124 B1

PDFFull Text
Date of Patent:
Jan. 10, 2023

Filed:

Sep. 20, 2018

Nepenthesin-1 derived resistance to fungal pathogens in major crop plants

Applicant:

Aarhus Universitet, Aarhus C, DK;

Inventors:

Zelalem Eshetu Bekalu, Aarhus V, DK;

Giuseppe Dionisio, Slagelse, DK;

Claus Krogh Madsen, Ringsted, DK;

Inger Bæksted Holme, København V, DK;

Thomas Povl Etzerodt, Hvidovre, DK;

Inge Fomsgaard, København V, DK;

Lise Nistrup Jørgensen, Slagelse, DK;

Henrik Brinch-Pedersen, Skælskør, DK;

Assignee:

AARHUS UNIVERSITET, Aarhus C, DK;

Attorneys:

Casimir Jones SC

Lisa Mueller

Primary Examiner:

Cathy Kingdom Worley

Int. Cl.
CPC ...
C12N 15/82 (2006.01); A23K 10/30 (2016.01); C12Q 1/68 (2018.01); C12N 9/50 (2006.01); C12Q 1/6895 (2018.01);
U.S. Cl.
CPC ...
C12N 15/8282 (2013.01); A23K 10/30 (2016.05); C12N 9/63 (2013.01); C12N 15/8234 (2013.01); C12Q 1/6895 (2013.01); C12Y 304/23 (2013.01); C12Y 304/23012 (2013.01);
Abstract

The invention relates to a genetically modified cereal plant having a recombinant DNA construct comprising a gene encoding a polypeptide having aspartyl protease activity (EC 3.4.23.12) whose expression, particularly in grain, confers enhanced fungal disease resistance as compared to a parent cereal plant from which said genetically modified cereal plant was derived. The invention further relates to a method for producing a genetically modified cereal plant of the invention comprising transforming one or more cells of a parent cereal plant with the recombinant DNA construct; as well as a method for manufacturing the genetically modified grain for production of a crop of genetically modified cereal plants which exhibit increased resistance to a fungal disease due to expression of the recombinant DNA construct. Furthermore, use of grain produced by a genetically modified cereal plant of the invention includes the manufacture of a composition, comprising a milled grain composition, an animal fodder, or steam-pelleted animal fodder.

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