The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 10, 2023

Filed:

Sep. 20, 2021
Applicant:

Landos Biopharma, Inc., Blacksburg, VA (US);

Inventors:

Josep Bassaganya-Riera, Blacksburg, VA (US);

Andrew Leber, Blacksburg, VA (US);

Nuria Tubau-Juni, Blacksburg, VA (US);

Raquel Hontecillas, Blacksburg, VA (US);

Assignee:

Landos Biopharma, Inc., Blacksburg, VA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/14 (2006.01); A61P 37/02 (2006.01);
U.S. Cl.
CPC ...
C07D 413/14 (2013.01);
Abstract

Provided are compounds that target the nucleotide-binding oligomerization domain, leucine rich repeat containing X1 (NLRX1) pathway. The compounds can be used to treat conditions such as autoimmune diseases, allergic diseases, chronic and/or inflammatory central nervous system diseases, chronic and/or inflammatory respiratory diseases, cancer, and infectious diseases. Exemplary conditions include multiple sclerosis, asthma, Alzheimer's disease, Parkinson's disease, neuroinflammation resulting from, for example, stroke, traumatic brain injury, or spinal cord injury, chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis, and inflammatory bowel disease.


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