The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 10, 2023
Filed:
Sep. 06, 2018
Applicant:
Hoffmann-la Roche Inc., Little Falls, NJ (US);
Inventors:
Zongxing Qiu, Shanghai, CN;
Hong Shen, Shanghai, CN;
Wei Zhu, Shanghai, CN;
Fabian Dey, Basel, CH;
Ge Zou, Shanghai, CN;
Hongtao Xu, Shanghai, CN;
Assignee:
Hoffmann-La Roche Inc., Little Falls, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/14 (2006.01); C07D 211/70 (2006.01); C07D 487/10 (2006.01);
U.S. Cl.
CPC ...
C07D 413/14 (2013.01); C07D 211/70 (2013.01); C07D 487/10 (2013.01);
Abstract
The present invention relates to compounds of formula (I), wherein R, Rand Rare as described herein, and their pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds as antagonist of TLR7 and/or TLR8 and/or TLR9 in the treatment of autoimmune diseases as well as auto-inflammation diseases.