The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 10, 2023

Filed:

Nov. 18, 2020
Applicant:

Bristol-myers Squibb Company, Princeton, NJ (US);

Inventors:

Andrew P. Degnan, Jamison, PA (US);

Godwin Kwame Kumi, Morrisville, PA (US);

Audris Huang, New Hope, PA (US);

James Aaron Balog, Lambertville, NJ (US);

Ashok Vinayak Purandare, Pennington, NJ (US);

Weifang Shan, Princeton, NJ (US);

Guo Li, Newtown, PA (US);

Assignee:

Bristol-Myers Squibb Company, Princeton, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 407/14 (2006.01); C07D 401/14 (2006.01); C07D 413/14 (2006.01); C07D 417/14 (2006.01); C07D 487/04 (2006.01); C07D 491/107 (2006.01); A61K 31/4439 (2006.01); A61P 35/00 (2006.01); C07D 405/14 (2006.01); C07D 498/18 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); C07D 405/14 (2013.01); C07D 417/14 (2013.01); C07D 487/04 (2013.01); C07D 498/18 (2013.01);
Abstract

Disclosed are compounds of Formula (I): or a salt thereof, wherein: Z is CRRor C═O; Ring A is: and R, R, R, R, R, m, and n are defined herein. Also disclosed are methods of using such compounds to inhibit Helios protein, and pharmaceutical compositions comprising such compounds. These compounds are useful in the treatment of viral infections and proliferative disorders, such as cancer.


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