The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 10, 2023
Filed:
Oct. 21, 2019
Cvergenx, Inc., St. Petersburg, FL (US);
Jacob G. Scott, Gates Mills, OH (US);
Javier Torres-Roca, St. Petersburg, FL (US);
CVERGENX, INC., St. Petersburg, FL (US);
Abstract
Disclosed herein are methods for personalized treatment of individual patient tumors. In one embodiment, a method of calculating a personalized radiation therapy dosage for a subject comprises determining expression levels of one or more signature genes from a subject's tumor sample, applying a linear regression model to the gene expression levels and assigning a radiation sensitivity index (RSI) to the subject's tumor sample, calculating a genomic adjusted radiation dose (GARD) value based on RSI, radiation dose and fractionation schedule of the subject, and calculating a personalized radiation dosage (RxRSI) for the subject based on a pre-determined GARD value.