The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 10, 2023

Filed:

Feb. 25, 2020
Applicant:

Corneagen Inc., Seattle, WA (US);

Inventors:

Edward J. Holland, Union, KY (US);

Kevin Potts, Lexington, NC (US);

Timothy G. Baldwin, Winston-Salem, NC (US);

Assignee:

CORNEAGEN INC., Seattle, WA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 27/36 (2006.01); A61F 2/14 (2006.01); A61F 9/007 (2006.01); A61F 9/013 (2006.01);
U.S. Cl.
CPC ...
A61L 27/3691 (2013.01); A61F 2/142 (2013.01); A61L 27/3604 (2013.01); A61F 9/007 (2013.01); A61F 9/0133 (2013.01); A61L 2430/16 (2013.01);
Abstract

A technique can consistently achieve thicknesses of ≤50 μm for corneal tissue for Descemet stripping automated endothelial keratoplasty (DSAEK). Grafts with thicknesses of ≤50 μm are also known as nanothin DSAEK (NT-DSAEK) grafts. Evidence shows that using thinner DSAEK grafts, particularly NT-DSAEK grafts, can significantly improve visual outcomes. According to an example embodiment, a method for producing a corneal graft includes drying a donor cornea to cause a pre-cut thickness of the donor cornea to decrease. The method includes, concurrently with drying the donor cornea, determining pre-cut thickness measurements for the donor cornea. The method includes, in response to the pre-cut thickness measurements indicating the pre-cut thickness of the donor cornea has decreased to a predetermined value, cutting the donor cornea to a post-cut thickness of ≤100 μm, or more particularly ≤50 μm, to produce a corneal graft.


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