The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 10, 2023

Filed:

Jan. 04, 2022
Applicant:

Boundless Bio, Inc., La Jolla, CA (US);

Inventors:

Christian Hassig, San Diego, CA (US);

Ryan Hansen, San Diego, CA (US);

Snezana Milutinovic, San Diego, CA (US);

Jason Christiansen, Carlsbad, CA (US);

Zachary Hornby, San Diego, CA (US);

Sudhir Chowdhry, San Diego, CA (US);

Anthony Celeste, San Diego, CA (US);

Kristen Turner, San Diego, CA (US);

Deepti Wilkinson, San Diego, CA (US);

Assignee:

BOUNDLESS BIO, INC., San Diego, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/517 (2006.01); A61P 35/00 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/517 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01);
Abstract

Provided herein are methods of treating cancer in a subject, wherein the cancer is extrachromosomal DNA-positive (ecDNA-positive) or therapeutically resistant, the method comprising administering to the subject a therapeutically effective amount of a replication stress (RS) pathway agent alone or in combination with a targeted therapeutic.


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