The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 10, 2023
Filed:
Dec. 26, 2018
St. Jude Children's Research Hospital, Inc., Memphis, TN (US);
Coa Therapeutics, Inc., San Francisco, CA (US);
Suzanne Jackowski, Bartlett, TN (US);
Charles O. Rock, Bartlett, TN (US);
Richard E. Lee, Cordova, TN (US);
Lalit Kumar Sharma, South San Francisco, CA (US);
Mi Kyung Yun, Collierville, TN (US);
Chitra Subramanian, Cordova, TN (US);
Rajendra P. Tangallapally, Collierville, TN (US);
Anne V. Edwards, Memphis, TN (US);
Robert Zamboni, Beaconsfield, CA;
T. Jagadeeswar Reddy, Pierrefonds, CA;
Jiuyu Liu, Collierville, TN (US);
ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC., Memphis, TN (US);
COA THERAPEUTICS, INC., San Francisco, CA (US);
Abstract
The present disclosure relates to methods of treating a coenzyme A reduction, elevation, sequestration, toxicity, or redistribution (CASTOR) disease such as, for example, defects in fatty acid oxidation enzymes, methylmalonic acidemia, glutaric acidemia, propionic academia, and HMG-CoA lyase, via small molecule modulators of CoA levels. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.