The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 10, 2023
Filed:
Mar. 05, 2020
Amneal Complex Products Research Llc, Bridgewater, NJ (US);
Siva Ram Kiran Vaka, Piscataway, NJ (US);
Atsawin Thongsukmak, Basking Ridge, NJ (US);
Jaydeep Vaghashiya, Franklin Park, NJ (US);
Dipen Desai, Whippany, NJ (US);
Navnit H. Shah, Monmouth Junction, NJ (US);
Wantanee Phuapradit, Lewes, DE (US);
Paras Jariwala, Somerset, NJ (US);
Amneal Complex Products Research LLC, Bridgewater, NJ (US);
Abstract
The present disclosure provides programmable osmotic-controlled oral compositions providing delayed extended release of a therapeutically acceptable amount of methylphenidate hydrochloride. The programmable osmotic-controlled compositions of the disclosure provide a lag time that is independent of the presence or absence of food, type of food, pH, gastric emptying, and volume of gastric fluid. The compositions of the disclosure can be programmed to provide a desired and precise lag time, and release drug, after the lag time, at a rhythm that matches the circadian rhythm of an individual being treated to optimize therapeutic outcome and minimize side effects.