The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 03, 2023
Filed:
Sep. 23, 2020
Applicant:
University of Maryland, Baltimore, Baltimore, MD (US);
Inventors:
Yihua (Bruce) Yu, Ellicott City, MD (US);
Marc B. Taraban, North Potomac, MD (US);
Assignee:
UNIVERSITY OF MARYLAND, BALTIMORE, Baltimore, MD (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 24/08 (2006.01); G01R 33/46 (2006.01); G01N 33/15 (2006.01);
U.S. Cl.
CPC ...
G01N 24/084 (2013.01); G01N 24/085 (2013.01); G01N 33/15 (2013.01); G01R 33/46 (2013.01);
Abstract
A method of using the transverse relaxation rate (R) of solvent NMR signal to detect filling errors of an alum-containing product in real-time in-line during manufacturing, for example during a fill-finish unit operation. This technique can be used for quality control in vaccine manufacturing to ensure the delivery of the correct concentration of alum-containing product to the product container such as a vial or pre-filled syringe.