The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 03, 2023
Filed:
Feb. 13, 2020
Applicant:
Iowa State University Research Foundation, Inc., Ames, IA (US);
Inventors:
Balaji Narasimhan, Ames, IA (US);
Surya Mallapragada, Ames, IA (US);
Anumantha G. Kanthasamy, Ames, IA (US);
Manohar John, Ames, IA (US);
Vellareddy Anantharam, Ames, IA (US);
Assignee:
Iowa State University Research Foundation, Inc., Ames, IA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/18 (2006.01); G01N 33/68 (2006.01); G01N 33/58 (2006.01);
U.S. Cl.
CPC ...
C07K 16/18 (2013.01); G01N 33/581 (2013.01); G01N 33/582 (2013.01); G01N 33/587 (2013.01); G01N 33/6896 (2013.01); C07K 2317/24 (2013.01); C07K 2317/33 (2013.01); C07K 2317/565 (2013.01); C07K 2317/92 (2013.01); G01N 2800/2821 (2013.01); G01N 2800/2835 (2013.01);
Abstract
Provided are aggregate alpha-synuclein specific antibodies as well as fragments, derivatives, and variants thereof as well as method related thereto for the early diagnostic and treatment of Parkinson's Disease and other Lewy body- and Lewy neurite-based diseases. Assays, kits, systems, and nanoparticle encapsulated compositions related to the antibodies or fragments, derivatives, and variants thereof are also disclosed.