The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 03, 2023

Filed:

Jul. 15, 2020
Applicant:

Salk Institute for Biological Studies, La Jolla, CA (US);

Inventors:

Ronald M. Evans, La Jolla, CA (US);

Michael Downes, San Diego, CA (US);

Annette Atkins, San Diego, CA (US);

Sihao Liu, San Diego, CA (US);

Ruth T. Yu, La Jolla, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/50 (2006.01); A61P 3/10 (2006.01); A61K 9/00 (2006.01); A61K 45/06 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/50 (2013.01); A61P 3/10 (2018.01); A61K 9/0019 (2013.01); A61K 38/00 (2013.01); A61K 45/06 (2013.01);
Abstract

The present disclosure provides FGF1 mutant proteins, which selectively bind to/activate FGFR1b. Also provided are nucleic acid molecules that encode such proteins, and vectors and cells that include such nucleic acids. Methods of using the disclosed FGF1 mutants to reduce blood glucose in a mammal and treat a metabolic disorder are provided.


Find Patent Forward Citations

Evans, Ronald. (2023). Fibroblast growth factor 1 (fgf1) mutant proteins that selectively activate fgfr1b to reduce blood glucose (U.S. Patent No. 11542309). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11542309

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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