The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 03, 2023
Filed:
Jun. 01, 2017
Applicant:
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Inventors:
Kevin Matthew Maloney, Piscataway, NJ (US);
Eric M. Sirota, Hoboken, NJ (US);
Richard J. Varsolona, Scotch Plains, NJ (US);
Donald R. Gauthier, Jr., Westfield, NJ (US);
Hong Ren, Green Brook, NJ (US);
Assignee:
Merck Sharp & Dohme LLC, Rahway, NJ (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 501/56 (2006.01); A61K 9/19 (2006.01); A61K 31/431 (2006.01); A61K 31/546 (2006.01);
U.S. Cl.
CPC ...
C07D 501/56 (2013.01); A61K 9/19 (2013.01); A61K 31/431 (2013.01); A61K 31/546 (2013.01); C07B 2200/13 (2013.01);
Abstract
The instant invention is related to a novel solid form of ceftolozane sulfate (the DMAc solvate of ceftolozane sulfate (Form 3)), compositions comprising ceftolozane sulfate DMAc solvate (Form 3), synthesis of Form 3 and an improved crystallization process using Form 3 to prepare ceftolozane sulfate Form 2. Novel compositions also include ceftolozane sulfate solid Form 3 and/or other crystalline and amorphous solid forms of ceftolozane.