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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11542275 B1

PDFFull Text
Date of Patent:
Jan. 03, 2023

Filed:

Mar. 20, 2019

Substituted imidazolidin-2-one derivatives as prmt5 inhibitors

Applicant:

Aurigene Discovery Technologies Limited, Bangalore, IN;

Inventors:

Dinesh Chikkanna, Bangalore, IN;

Sunil Kumar Panigrahi, Boudh, IN;

Srinivasa Raju Sammeta, Bangalore, IN;

Assignee:

AURIGENE DISCOVERY TECHNOLOGIES LIMITED, Bangalore, IN;

Attorneys:

Dennemeyer & Associates

Steven M. Shape

Primary Examiner:

Samantha L Shterengarts

Int. Cl.
CPC ...
C07D 498/08 (2006.01); C07D 401/14 (2006.01); C07D 405/14 (2006.01); C07D 413/14 (2006.01); C07D 471/08 (2006.01); C07D 487/04 (2006.01); C07D 491/107 (2006.01); C07D 493/08 (2006.01); C07D 495/04 (2006.01);
U.S. Cl.
CPC ...
C07D 498/08 (2013.01); C07D 401/14 (2013.01); C07D 405/14 (2013.01); C07D 413/14 (2013.01); C07D 471/08 (2013.01); C07D 487/04 (2013.01); C07D 491/107 (2013.01); C07D 493/08 (2013.01); C07D 495/04 (2013.01);
Abstract

The present invention relates to substituted imidazolidin-2-one derivatives of formula (I) or pharmaceutically acceptable salts thereof. The present invention further provides the methods of preparation of compound of formula (I) and utility as PRMT5 inhibitors. The compounds are useful as medicaments in the treatment of conditions and disorders mediated by PRMT5, such as cancer, metabolic disorders, inflammation, autoimmune disease and hemoglobinopathies.

Find Patent Forward Citations

Chikkanna, Dinesh. (2023). Substituted imidazolidin-2-one derivatives as prmt5 inhibitors (U.S. Patent No. 11542275). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11542275

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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