The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 03, 2023

Filed:

Jul. 04, 2019
Applicant:

Mitsubishi Tanabe Pharma Corporation, Osaka, JP;

Inventors:

Ryuta Yamazaki, Tokyo, JP;

Tatsuya Ibuki, Tokyo, JP;

Yuichi Sawaguchi, Tokyo, JP;

Kiyomi Ohba, Osaka, JP;

Maiko Hamada, Osaka, JP;

Yasuki Niwa, Osaka, JP;

Yuko Ishida, Osaka, JP;

Hideto Maruyama, Osaka, JP;

Shiki Matsuki, Osaka, JP;

Minoru Tanaka, Osaka, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 495/14 (2006.01); A61P 35/02 (2006.01);
U.S. Cl.
CPC ...
C07D 495/14 (2013.01); A61P 35/02 (2018.01);
Abstract

Provided are a compound superior in a cytotoxic action on cancer cells, an action inducing degradation of BET protein in cancer cells, and an inhibitory action on the binding of BET protein and acetylated histone, and useful as an anticancer agent, a BET protein degradation inducer or a BET protein inhibitor. A compound represented by the following formula (I) wherein each symbol is as defined in the specification, or a pharmacologically acceptable salt thereof.


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