The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 03, 2023
Filed:
Mar. 18, 2019
Applicant:
Purdue Research Foundation, West Lafayette, IN (US);
Inventors:
Vincent Jo Davisson, West Lafayette, IN (US);
Aaron Raymond Lindstrom, Lafayette, IN (US);
Assignee:
Purdue Research Foundation, West Lafayette, IN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 405/14 (2006.01); A61P 31/12 (2006.01); A61K 9/14 (2006.01); C07D 405/04 (2006.01); C07D 407/04 (2006.01); C07D 409/14 (2006.01); C07D 413/14 (2006.01);
U.S. Cl.
CPC ...
C07D 405/14 (2013.01); A61K 9/14 (2013.01); A61P 31/12 (2018.01); C07D 405/04 (2013.01); C07D 407/04 (2013.01); C07D 409/14 (2013.01); C07D 413/14 (2013.01);
Abstract
Ebola virus and Marburg virus are filoviruses and are responsible for outbreaks that cause up to 90% fatality, including the recent outbreak in West Africa that has resulted in over 11,000 deaths. The present disclosure generally relates to novel arylnaphthalene compounds as a vacuolar-ATPase inhibitor that are useful for the treatment of various viral infections, including those infections caused by filoviruses. Pharmaceutical composition matters and methods of use are within the scope of this invention.