The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 03, 2023
Filed:
Jan. 15, 2020
Applicant:
The Board of Regents of the University of Texas System, Austin, TX (US);
Inventors:
Daniel J. Siegwart, Dallas, TX (US);
Jason B. Miller, Dallas, TX (US);
Assignee:
The Board of Regents of The University of Texas System, Austin, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 311/32 (2006.01); C12N 15/88 (2006.01); C07F 9/09 (2006.01); C07F 9/10 (2006.01); C12N 15/11 (2006.01); B82Y 5/00 (2011.01); C07C 229/06 (2006.01); A61K 47/69 (2017.01); A61K 47/54 (2017.01); A61K 48/00 (2006.01); C07C 309/14 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C07C 311/32 (2013.01); A61K 47/543 (2017.08); A61K 47/6911 (2017.08); A61K 48/0033 (2013.01); B82Y 5/00 (2013.01); C07C 229/06 (2013.01); C07C 309/14 (2013.01); C07F 9/091 (2013.01); C07F 9/106 (2013.01); C12N 15/11 (2013.01); C12N 15/111 (2013.01); C12N 15/113 (2013.01); C12N 15/88 (2013.01); C12N 2310/14 (2013.01); C12N 2310/20 (2017.05); C12N 2320/32 (2013.01);
Abstract
The present disclosure provides one or more amino lipids such as an amino lipids containing a sulfonic acid or sulfonic acid derivative of the formulas: wherein the variables are as defined herein. These amino lipids may be used in compositions with one or more helper lipids and a nucleic acid therapeutic agent. These compositions may be used to treat a disease or disorder such as cancer, cystic fibrosis, or other genetic diseases.