The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 03, 2023

Filed:

Jun. 13, 2019
Applicant:

Texas Tech University System, Lubbock, TX (US);

Inventors:

Susan E. Bergeson, Lubbock, TX (US);

Peter Syapin, Camarillo, CA (US);

Ted W. Reid, Lubbock, TX (US);

Mayank Shashtri, Lubbock, TX (US);

Phat Tran, Lubbock, TX (US);

Assignee:

Texas Tech University System, Lubbock, TX (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/65 (2006.01); C07C 237/26 (2006.01); A61B 5/00 (2006.01); C07D 317/72 (2006.01);
U.S. Cl.
CPC ...
C07C 237/26 (2013.01); A61B 5/4848 (2013.01); A61K 31/65 (2013.01); C07D 317/72 (2013.01); C07C 2603/46 (2017.05);
Abstract

A method of treating Alcohol Use Disorder (AUD), Substance Use Disorder (SUD), tobacco use, pain, or proinflammatory disorders comprising: providing a subject with an effective amount of a modified tetracycline or derivative thereof to ameliorate or eliminate the AUD, SUD, tobacco use, pain, or proinflammatory disorder, and wherein the modified tetracycline or derivative thereof has reduced binding to a microbial ribosome and has the formula wherein R1 is acetyl, R2 is OH or acetyl, R3 is acetyl, R4 is H or acetyl, and R5 is acetyl.


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