The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 03, 2023

Filed:

Nov. 21, 2019
Applicants:

Massachusetts Institute of Technology, Cambridge, MA (US);

The Brigham and Women's Hospital, Inc., Boston, MA (US);

Novo Nordisk A/s, Bagsvaerd, DK;

Inventors:

Carlo Giovanni Traverso, Newton, MA (US);

Morten Revsgaard Frederiksen, Bagsvaerd, DK;

Jorrit Jeroen Water, Frederiksberg, DK;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61M 37/00 (2006.01); A61K 9/16 (2006.01); A61M 31/00 (2006.01);
U.S. Cl.
CPC ...
A61M 37/0069 (2013.01); A61K 9/16 (2013.01); A61M 31/002 (2013.01); A61M 2202/0007 (2013.01); A61M 2202/06 (2013.01); A61M 2207/10 (2013.01);
Abstract

Methods of manufacturing tissue interfacing components, such as solid needles comprising one or more therapeutic agents, are disclosed. In some embodiments, a method for manufacturing a tissue interfacing component comprises compressing a granular therapeutic agent within a mold cavity of a mold to form a solid tissue interfacing component. The mold cavity may define an elongated shape extending along a longitudinal axis from an opening of the mold cavity to a distal end of the mold cavity, and the granular therapeutic agent may be compressed by moving a mold punch along the longitudinal axis towards the distal end. After compressing the granular therapeutic agent to form the solid tissue interfacing component, the tissue interfacing component may be removed from the mold and subsequently inserted into tissue to deliver the therapeutic agent to a subject.


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