The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 03, 2023

Filed:

Nov. 14, 2018
Applicant:

Lutonix, Inc., Franklin Lakes, NJ (US);

Inventors:

Robert E. Burgmeier, Franklin Lakes, NJ (US);

Oleg Stanilevskiy, Franklin Lakes, NJ (US);

Jeffrey Wang, Franklin Lakes, NJ (US);

Assignee:

Other;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61L 29/14 (2006.01); A61K 31/337 (2006.01); A61L 29/08 (2006.01); A61M 25/00 (2006.01); B05D 3/14 (2006.01);
U.S. Cl.
CPC ...
A61L 29/148 (2013.01); A61K 31/337 (2013.01); A61L 29/085 (2013.01); A61M 25/0009 (2013.01); B05D 3/142 (2013.01); A61L 2300/216 (2013.01); A61L 2300/802 (2013.01); A61L 2400/18 (2013.01); A61L 2420/02 (2013.01); A61L 2420/08 (2013.01);
Abstract

Medical devices such as stents, stent grafts, and balloon catheters include a coating layer applied over a modified exterior surface of the medical device. The modified exterior surface comprises an exterior surface of the medical device subjected to a surface modification that decreases a surface free energy of the exterior surface before application of the coating layer an exterior surface. The coating layer comprises a hydrophobic therapeutic agent and at least one additive. The modified exterior surface may affect the release kinetics of the drug from the device, the crystallinity of the drug layer, the surface morphology of the coating and particle shape, or the particle size of drug of a therapeutic layer in the coating layer. For example, the effects caused by the modified exterior surface may increase the retention time and amount of therapeutic agent in tissue.


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