The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 03, 2023
Filed:
Jan. 12, 2018
Radiomedix Inc., Houston, TX (US);
Orano Med, Courbevoie, FR;
Izabela Tworowska, Houston, TX (US);
Nilesh Wagh, Houston, TX (US);
Ebrahim S. Delpassand, Houston, TX (US);
Federico Rojas-Quijano, Bedford, TX (US);
Paul Jurek, Red Oak, TX (US);
Garry E. Kiefer, Richardson, TX (US);
Tania A. Stallons, Wylie, TX (US);
Amal Saidi, Thomon-les-Bains., FR;
Julien Torgue, Gaithersburg, MD (US);
RADIOMEDIXINC., Houston, TX (US);
ORANO MED, Courbevoie, FR;
Abstract
A cancer targeting composition, kit, and method for treatment of cancer cells overexpressing somatostatin receptors is disclosed. The composition includes a radioisotope, a chelator, and a targeting moiety. The chelator includes a nitrogen ring structure including a tetraazacyclododecane, a triazacyclononane, and/or a tetraazabicyclo [6.6.2] hexadecane derivative. The targeting moiety includes a somatostatin receptor targeting peptide. The somatostatin receptor targeting peptide includes an octreotide derivative. The targeting moiety is chelated to the radioisotope by the chelator whereby the cancer cells are targeted for elimination.