The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 03, 2023
Filed:
Mar. 16, 2020
Northwestern University, Evanston, IL (US);
Consejo Nacional DE Investigaciones Científicas Y Técnicas, Buenos Aires, AR;
Universidade Federal DO Rio DE Janeiro, Rio de Janeiro, BR;
William L. Klein, Winnetka, IL (US);
Diana Jerusalinsky, Buenos Aires, AR;
Sergio T. Ferreira, Rio de Janeiro, BR;
Maria Clara Selles, Rio de Janeiro, BR;
Adriano S. Sebollela, Rio de Janeiro, BR;
Northwestern Univeristy, Evanston, IL (US);
Abstract
Provided herein are antibodies against amyloid-beta (Aβ) oligomers, and methods of use thereof for the treatment of Alzheimer's disease (AD). In particular, neuronal expression of single-chain variable fragment (scFv) antibodies against Aβ oligomers is provided as a therapeutic approach in the treatment of AD.