The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 03, 2023
Filed:
Dec. 13, 2019
Amgen Inc., Thousand Oaks, CA (US);
Santa Maria Biotherapeutics, Inc., South San Francisco, CA (US);
Huiquan Han, Thousand Oaks, CA (US);
Christopher Michael Haqq, Newbury Park, CA (US);
Isaac Ciechanover, Burlingame, CA (US);
Xiaolan Zhou, Newbury Park, CA (US);
John Zhao-Nian Lu, Alhambra, CA (US);
Atara Biotherapeutics, Inc., South San Francisco, CA (US);
Abstract
The present invention relates to methods of treating ovarian cancer in a subject by administering to the subject by evaluating the subject's expression levels of specific biomarkers or angiogenic an anti-activin-A compound, such as an anti-activin-A antibody or an activin-A-binding receptor. In some embodiments, at least two compounds are administered to the subject, where the first compound is an anti-activin A compound, and the second compound is a chemotherapeutic compound, for example capecitabine. The invention further relates to methods of identifying subjects for treatment factors.