The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 03, 2023

Filed:

Mar. 18, 2019
Applicant:

Sichuan Kelun-biotech Biopharmaceutical Co., Ltd., Sichuan, CN;

Inventors:

Yongyong Wu, Sichuan, CN;

Jiaqiang Cai, Sichuan, CN;

Guangchao Zhang, Sichuan, CN;

Shuangshuang Duan, Sichuan, CN;

Chaolei Wang, Sichuan, CN;

Lichun Wang, Sichuan, CN;

Jingyi Wang, Sichuan, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/14 (2006.01); A61K 31/496 (2006.01); A61P 7/02 (2006.01); A61K 31/4725 (2006.01); A61K 45/06 (2006.01); C07D 401/14 (2006.01); C07D 413/14 (2006.01); C07D 401/10 (2006.01);
U.S. Cl.
CPC ...
A61K 31/496 (2013.01); A61K 31/4725 (2013.01); A61K 45/06 (2013.01); A61P 7/02 (2018.01); C07D 401/10 (2013.01); C07D 401/14 (2013.01); C07D 403/14 (2013.01); C07D 413/14 (2013.01);
Abstract

Provided are tetrahydroisoquinoline derivatives, the preparation and use thereof. More specifically, provided are the tetrahydroisoquinoline derivatives or a pharmaceutically acceptable salt, ester, stereoisomer, tautomer, polymorph, solvate, isotopically labeled compound, metabolite or prodrug thereof. Further provided are a preparation process of the compound, the intermediates, a pharmaceutical composition comprising the compound and the use thereof in the treatment or prevention of a thromboembolic disorder.


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