The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 03, 2023
Filed:
Jun. 29, 2018
Yusheng Xiong, Plainsboro, NJ (US);
Hong-ping Guan, Scotch Plains, NJ (US);
Wenjun Huang, Doylestown, PA (US);
Quixgen, Inc., North Brunswick, NJ (US);
Yusheng Xiong, Plainsboro, NJ (US);
Hong-Ping Guan, Scotch Plains, NJ (US);
Wenjun Huang, Doylestown, PA (US);
Quixgen, Inc., North Brunswick, NJ (US);
Abstract
Provided herein are spirolactone compounds of Formula I that are useful as inhibitors of ACC1 and/or ACC2. The spirolactone compounds described herein can be used for treating a disease or disorder associated with aberrant ACC1 and/or ACC2 activities, for example, non-alcoholic steatohepatitis (NASH), acne, obesity, diabetes, and cancer. Also provided herein are pharmaceutical compositions comprising the spirolactone compound of Formula I, or pharmaceutically acceptable salt thereof.