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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11541041 B1

PDFFull Text
Date of Patent:
Jan. 03, 2023

Filed:

Jul. 12, 2021

Compounds that interact with the ras superfamily for the treatment of cancers, inflammatory diseases, rasopathies, and fibrotic disease

Applicant:

Shy Therapeutics Llc, Harrison, NY (US);

Inventors:

Yaron R. Hadari, Harrison, NY (US);

Luca Carta, Scarsdale, NY (US);

Michael Schmertzler, St. Petersburg, FL (US);

Theresa M. Williams, Harleysville, PA (US);

Charles H. Reynolds, Austin, TX (US);

Rebecca Hutcheson, Stamford, CT (US);

Assignee:

SHY Therapeutics LLC, Harrison, NY (US);

Attorney:

Jones Day

Primary Examiner:

Yih-Horng Shiao

Int. Cl.
CPC ...
A61K 31/4365 (2006.01); C12N 15/10 (2006.01); A61P 35/00 (2006.01); A61P 29/00 (2006.01); C07K 14/435 (2006.01); C07D 495/04 (2006.01); A61K 31/505 (2006.01); A61P 25/28 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4365 (2013.01); A61K 31/505 (2013.01); A61P 25/28 (2018.01); A61P 29/00 (2018.01); A61P 35/00 (2018.01); C07D 495/04 (2013.01); C07K 14/435 (2013.01); C12N 15/1037 (2013.01); C12N 15/1065 (2013.01);
Abstract

Provided herein are methods and compositions for treating cancers, inflammatory diseases, rasopathies, and fibrotic disease involving aberrant Ras superfamily signaling through the binding of compounds to the GTP binding domain of Ras superfamily proteins including, in certain cases, K-Ras and mutants thereof, and a novel method for assaying such compositions.

Find Patent Forward Citations

Hadari, Yaron. (2023). Compounds that interact with the ras superfamily for the treatment of cancers, inflammatory diseases, rasopathies, and fibrotic disease (U.S. Patent No. 11541041). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11541041

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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