The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 03, 2023
Filed:
May. 04, 2020
Applicant:
Biontech Delivery Technologies Gmbh, Halle, DE;
Inventors:
Steffen Panzner, Halle, DE;
Evgenios Siepi, Frenaros, CY;
Assignee:
BioNTech Delivery Technologies GmbH, Halle, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/127 (2006.01); C12N 15/88 (2006.01); C07D 233/61 (2006.01); C07C 279/14 (2006.01); C07C 237/22 (2006.01); C07C 233/36 (2006.01); C07C 233/43 (2006.01); C07C 279/12 (2006.01); C07D 213/75 (2006.01); C07J 41/00 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 9/1272 (2013.01); C07C 233/36 (2013.01); C07C 233/43 (2013.01); C07C 237/22 (2013.01); C07C 279/12 (2013.01); C07C 279/14 (2013.01); C07D 213/75 (2013.01); C07D 233/61 (2013.01); C07J 41/0055 (2013.01); C12N 15/1137 (2013.01); C12N 15/88 (2013.01); C12N 2310/14 (2013.01); C12N 2320/32 (2013.01); Y02P 20/582 (2015.11);
Abstract
The invention concerns lipid assemblies, liposomes having an outer surface comprising a mixture of anionic and cationic moieties; wherein at least a portion of the cationic moieties are imino moieties that are essentially charged under physiological conditions, and their use for serum resistant transfection of cells.