The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 03, 2023

Filed:

Feb. 08, 2018
Applicant:

New Hope Research Foundation, North Oaks, MN (US);

Inventor:

John G. Keimel, North Oaks, MN (US);

Assignee:

New Hope Research Foundation, Inc., North Oaks, MN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61M 25/01 (2006.01); A61K 31/7088 (2006.01); A61M 27/00 (2006.01); A61M 25/00 (2006.01); A61M 25/02 (2006.01);
U.S. Cl.
CPC ...
A61K 9/0085 (2013.01); A61K 31/7088 (2013.01); A61M 25/0102 (2013.01); A61M 27/006 (2013.01); A61M 2025/0063 (2013.01); A61M 2025/0293 (2013.01);
Abstract

Aspects herein relate to systems and methods for delivery of biologic agents to the central nervous system. In various embodiments, a method of administering a therapeutic agent to the central nervous system (CNS) is included. The method can include injecting a therapeutic agent into a first cerebrospinal fluid (CSF) region of the subject. The method can further include establishing fluid communication between a fluid reservoir and a second cerebrospinal fluid (CSF) region of a subject, the fluid having a hydraulic pressure at or above an intracranial pressure. The method can further include infusing a hyperosmotic fluid systemically. Other embodiments, including kits and systems are also included herein.


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