The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 03, 2023

Filed:

May. 03, 2019
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Zhongping Chen, Irvine, CA (US);

Youmin He, Irvine, CA (US);

Yueqiao Qu, Irvine, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 3/14 (2006.01); A61B 3/12 (2006.01); A61B 8/10 (2006.01); A61B 8/08 (2006.01); A61B 8/00 (2006.01); G06T 7/12 (2017.01); A61B 5/00 (2006.01); G06K 9/62 (2022.01); A61B 3/10 (2006.01);
U.S. Cl.
CPC ...
A61B 3/1225 (2013.01); A61B 3/102 (2013.01); A61B 3/14 (2013.01); A61B 5/7264 (2013.01); A61B 8/10 (2013.01); A61B 8/4488 (2013.01); A61B 8/4494 (2013.01); A61B 8/485 (2013.01); A61B 8/488 (2013.01); A61B 8/5261 (2013.01); G06K 9/6224 (2013.01); G06T 7/12 (2017.01); G06T 2207/10101 (2013.01); G06T 2207/10132 (2013.01); G06T 2207/20081 (2013.01); G06T 2207/20116 (2013.01); G06T 2207/20221 (2013.01); G06T 2207/30041 (2013.01);
Abstract

Retinal diseases, such as age-related macular degeneration (AMD), are the leading cause of blindness in the elderly population. Since no known cures are currently present, it is crucial to diagnose the condition in its early stages so that disease progression is monitored. Systems and methods for detecting and mapping the mechanical elasticity of retinal layers in the posterior eye are disclosed herein. A system including confocal shear wave acoustic radiation force optical coherence elastography (SW-ARF-OCE) is provided, wherein an ultrasound transducer and an optical scan head are co-aligned to facilitate in-vivo study of the retina. In addition, an automatic segmentation algorithm is used to isolate tissue layers and analyze the shear wave propagation within the retinal tissue to estimate mechanical stress on the retina and detect early stages of retinal diseases based on the estimated mechanical stress.


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