The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 27, 2022

Filed:

Dec. 17, 2021
Applicant:

Proteinsimple, San Jose, CA (US);

Inventors:

Jiaqi Wu, San Jose, CA (US);

Christopher Heger, San Jose, CA (US);

Assignee:

ProteinSimple, San Jose, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 1/00 (2006.01); C07K 1/14 (2006.01); C12N 9/80 (2006.01); C12N 9/82 (2006.01); C12Q 1/70 (2006.01); G16B 20/00 (2019.01);
U.S. Cl.
CPC ...
C12Q 1/70 (2013.01); G16B 20/00 (2019.02);
Abstract

Embodiments disclosed include systems, devices, and methods for analysis of samples containing particles used for gene delivery to determine a quality of the sample and/or an indication that the gene delivery particles are in a full, partial, and/or empty state. The present disclosure also relates to determining a protein and/or NA content in samples with known proportions of gene delivery particles in a full, partial, and/or empty state and based on the determination, establish a relationship between NA content and proportions of gene delivery particles in a full state. The present disclosure also relates to using such an established relationship to predict a proportion of the gene delivery particles in a full, partial, and/or empty state in test samples having the gene delivery particles in an unknown state.


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