The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 27, 2022
Filed:
Oct. 21, 2013
Applicant:
Genomatica, Inc., San Diego, CA (US);
Inventors:
Anthony P. Burgard, Bellefonte, PA (US);
Robin E. Osterhout, San Diego, CA (US);
Stephen J. Van Dien, Encinitas, CA (US);
Cara Ann Tracewell, Solana Beach, CA (US);
Priti Pharkya, San Diego, CA (US);
Stefan Andrae, San Diego, CA (US);
Assignee:
Genomatica, Inc., San Diego, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/96 (2006.01); C12P 7/46 (2006.01); C12N 9/04 (2006.01); C12N 9/06 (2006.01); C12N 9/10 (2006.01); C07C 55/10 (2006.01); C08G 63/00 (2006.01); C12N 15/70 (2006.01); C12N 15/81 (2006.01); C12P 7/24 (2006.01); C07C 59/235 (2006.01); C12N 15/74 (2006.01); C12N 15/77 (2006.01);
U.S. Cl.
CPC ...
C12P 7/46 (2013.01); C07C 55/10 (2013.01); C07C 59/235 (2013.01); C08G 63/00 (2013.01); C12N 9/0006 (2013.01); C12N 9/0028 (2013.01); C12N 9/1007 (2013.01); C12N 15/70 (2013.01); C12N 15/74 (2013.01); C12N 15/77 (2013.01); C12N 15/81 (2013.01); C12N 15/815 (2013.01); C12P 7/24 (2013.01); C12Y 101/01244 (2013.01); C12Y 105/0102 (2013.01);
Abstract
Provided herein is a non-naturally occurring microbial organism (NNOMO) having a methanol metabolic pathway (MMP) that can enhance the availability of reducing equivalents in the presence of methanol. Such reducing equivalents can be used to increase the product yield of organic compounds produced by the microbial organism, such as succinate. Also provided herein are methods for using such an organism to produce succinate.