The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 27, 2022
Filed:
May. 05, 2017
Applicant:
Benitec Biopharma Limited, North Sydney, AU;
Inventors:
Tin Mao, San Bruno, CA (US);
David Suhy, San Ramon, CA (US);
Assignee:
Benitec IP Holdings Inc., New Castle, DE (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); A61K 31/513 (2006.01); A61K 31/522 (2006.01); A61K 31/675 (2006.01); A61K 38/21 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1131 (2013.01); A61K 31/513 (2013.01); A61K 31/522 (2013.01); A61K 31/675 (2013.01); A61K 38/21 (2013.01); C12N 2310/141 (2013.01); C12N 2310/531 (2013.01); C12N 2330/51 (2013.01);
Abstract
This disclosure relates to RNA interference (RNAi) reagents for treatment of hepatitis B virus (HBV) infection, compositions comprising same, and use thereof to treat individuals infected with HBV. The reagents are artificial miRNA (shmiRNA) used alone or in combination with additional shmiRNA or shRNA.