The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 27, 2022
Filed:
Dec. 13, 2018
Glaxosmithkline Intellectual Property Development Limited, Brentford, GB;
Kristin K. Brown, Collegeville, PA (US);
Brent M. Dorr, Collegeville, PA (US);
Douglas E. Fuerst, Collegeville, PA (US);
Katherine Joyce Honicker, Collegeville, PA (US);
Lydia Sanchez Jordan, Collegeville, PA (US);
James Patrick Morrison, Collegeville, PA (US);
Nikolay V. Plotnikov, Collegeville, PA (US);
Markus Schober, Stevenage, GB;
Rama Voladri, Redwood City, CA (US);
GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED, Brentford, GB;
Abstract
The present disclosure provides engineered carboxyesterase enzymes that have the ability to catalyze amide bond formation. Also provided are polynucleotides encoding the carboxyesterase enzymes, host cells capable of expressing the engineered carboxyesterase enzymes, and methods of using the engineered carboxyesterase enzymes to make commercially valuable amides. Also provided are amides that are made using the engineered carboxyesterase enzymes.