The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 27, 2022
Filed:
May. 09, 2018
Applicant:
Massachusetts Institute of Technology, Cambridge, MA (US);
Inventors:
Daniela Espinosa-Hoyos, Cambridge, MA (US);
Anna E. Jagielska, Topsfield, MA (US);
Huifeng Du, Cambridge, MA (US);
Nicholas X. Fang, Lexington, MA (US);
Krystyn J. Van Vliet, Lexington, MA (US);
Assignee:
MASSACHUSETTS INSTITUTE OF TECHNOLOGY, Cambridge, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/079 (2010.01); G01N 33/50 (2006.01); B29C 64/135 (2017.01); B33Y 70/00 (2020.01); C12M 1/00 (2006.01); C12M 1/12 (2006.01); B29L 31/00 (2006.01); B29K 83/00 (2006.01); B29K 33/04 (2006.01); B33Y 10/00 (2015.01);
U.S. Cl.
CPC ...
C12N 5/0622 (2013.01); B29C 64/135 (2017.08); B33Y 70/00 (2014.12); C12M 23/20 (2013.01); C12M 25/02 (2013.01); G01N 33/5058 (2013.01); B29K 2033/04 (2013.01); B29K 2083/00 (2013.01); B29L 2031/7532 (2013.01); B33Y 10/00 (2014.12); C12N 2533/30 (2013.01); C12N 2535/00 (2013.01); C12N 2539/00 (2013.01);
Abstract
Materials and methods for cell-mimetics having mechanical properties of biological neural axons are provided. A cell-mimetic device includes an array of fibers comprised of hexanediol diacrylate (HDDA) or an HDDA derivative, and at least one derivative of polyethylene glycol (PEG) selected from the group consisting of: PEG-acrylate, PEG-diacrylate, and any multi-arm PEG-acrylate.