The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 27, 2022
Filed:
Dec. 14, 2018
Applicant:
Bluebird Bio, Inc., Cambridge, MA (US);
Inventor:
Olivier Negre, Cambridge, MA (US);
Assignee:
Bluebird Bio, Inc., Cambridge, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/34 (2006.01);
U.S. Cl.
CPC ...
C07K 16/34 (2013.01); C07K 2317/565 (2013.01); C07K 2317/622 (2013.01);
Abstract
The invention generally provides improved anti-sickled-globin antibodies and fragments thereof. In particular embodiments, the antibody or antigen binding fragment thereof recognizes the βs, Glu6Val mutation. In various embodiments, the invention provides a conjugate comprising an anti-βs-globin antibody or antigen binding fragment thereof and a detectable label. In particular embodiments, a hybridoma comprising an anti-βs-globin antibody contemplated herein is provided.