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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11535669 B1

PDFFull Text
Date of Patent:
Dec. 27, 2022

Filed:

Jul. 09, 2019

Fusion constructs and methods of using thereof

Applicant:

Precigen, Inc., Blacksburg, VA (US);

Inventors:

Helen Sabzevari, Blacksburg, VA (US);

Simon Metenou, Blacksburg, VA (US);

ChangHung Chen, Blacksburg, VA (US);

Rutul R. Shah, Blacksburg, VA (US);

Assignee:

PRECIGEN, INC., Germantown, MD (US);

Attorneys:

Gene J. Yao

Barnes & Thornburg LLP

Primary Examiner:

Vanessa L Ford

Assistant Examiner:

Sandra Dillahunt

Int. Cl.
CPC ...
C07K 16/28 (2006.01); C07K 14/71 (2006.01); C07K 16/22 (2006.01); A61K 39/00 (2006.01); A61P 35/00 (2006.01); A61K 35/17 (2015.01);
U.S. Cl.
CPC ...
C07K 16/2818 (2013.01); A61K 35/17 (2013.01); A61P 35/00 (2018.01); C07K 14/71 (2013.01); C07K 16/22 (2013.01); A61K 2039/505 (2013.01); C07K 2317/56 (2013.01); C07K 2317/92 (2013.01); C07K 2319/00 (2013.01);
Abstract

Provided herein is a composition comprising a fusion protein or a fragment or a variant thereof comprising an anti-PD1 antibody or a fragment/variant thereof and a TGF-β trap. Provided herein is a composition comprising a fusion protein or a fragment thereof or a variant thereof comprising an anti-PD1 antibody or a fragment/variant thereof and a ADA2 polypeptide. Also provided herein are methods of using the composition in treating cancer.

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Sabzevari, Helen. (2022). Fusion constructs and methods of using thereof (U.S. Patent No. 11535669). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11535669

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